Transcription Gets to the Checkpoint

نویسندگان

  • John D. Laver
  • Howard D. Lipshitz
چکیده

The rapid cell proliferation characteristic of early animal embryos is accomplished with an abbreviated cell cycle and no DNA replication checkpoint. Blythe and Wieschaus provide evidence that nascent zygotic transcription precedes—and may trigger—this checkpoint at the midblastula transition.

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عنوان ژورنال:
  • Cell

دوره 160  شماره 

صفحات  -

تاریخ انتشار 2015